Actos May Help Slow Heart Disease

According to a new study, the Type 2 diabetes drug pioglitazone (brand name Actos) appears to slow the progression of coronary atherosclerosis, or narrowing of the heart’s arteries due to plaque buildup, better than an older diabetes drug, glimepiride (Amaryl, also available generically). People who have diabetes are at increased risk of developing heart disease, and coronary atherosclerosis can lead to angina or heart attack. Read More “Actos May Help Slow Heart Disease”

Weight, Prejudice, and Type 2 Diabetes

Do you think overweight people bring Type 2 diabetes on themselves? It would be natural to think that, because doctors and other authorities have been blaming weight for years. Health "experts” call Type 2 a "lifestyle disease," implying that people choose it. Heavy people are called "obese," which comes from the Latin for "over/eating," as if that were the whole cause of overweight. Read More “Weight, Prejudice, and Type 2 Diabetes”

ADVANCE Study Contradicts ACCORD Findings

The surprising and much-publicized early findings from the ACCORD study, which showed a slightly increased risk of death among certain people with Type 2 diabetes who used intensive drug therapy to lower blood glucose levels, have prompted researchers conducting a similar ongoing study to release early results. The ADVANCE study, which is the largest study ever of aggressive blood glucose control in people with Type 2 diabetes, has found no increase in risk of death associated with intensive treatment. Read More “ADVANCE Study Contradicts ACCORD Findings”

Gastric Banding May Help Reverse Type 2

A study published in January in The Journal of the American Medical Association found that gastric banding weight-loss surgery in obese people with Type 2 diabetes led to better blood glucose control and higher rates of diabetes reversal than lifestyle changes meant to help people lose weight. The surgery also helped people lose significantly more weight than lifestyle changes. This was the first randomized study comparing weight-loss surgery to conventional therapy for managing Type 2 diabetes in obese people. Read More “Gastric Banding May Help Reverse Type 2”

The ACCORD Trial Findings: What You Should Know

In one large, ongoing trial of people with Type 2 diabetes and a high risk of cardiovascular disease, intensive blood glucose control has been linked with a slightly higher risk of death compared with less-intensive, "standard" treatment. Participants in the trial who were receiving intensive treatment will now be switched over to standard treatment. While these findings were unexpected and have raised some concerns about diabetes treatment strategies for specific groups of people, they should not trigger a change in therapy for most people with diabetes. Read More “The ACCORD Trial Findings: What You Should Know”


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